The Office of the Principal Scientific Adviser to the Government of India, on May 20,2021, issued a simple and easy to follow guideline to “Stop the Transmission, Crush the Pandemic - Masks, distance, sanitation and ventilation to prevent the spread of SARS-CoV-2 virus”. The advisory highlights the simple tools and practices that can reduce the spread of SARS-CoV-2 virus. Along with the best practices like wearing masks, washing hands frequently and maintain social distance, the advisory comprehensively highlights the important role well-ventilated spaces play in diluting the viral load of infected air in houses, offices etc.